Charo has made several appearances on RuPaul's Drag Race over the years, contributing her signature humor and flamboyant style to the show. In 2009, she appeared on the "Absolut Drag Ball" episode, offering playful advice to contestants, such as, "Be careful! Spooning leads to forking," and "Chin is up. Stomach is in. Even if you don't breathe, never mind. If you drop dead, you drop dead with class." These quips showcased her comedic timing and understanding of the show's campy tone.

In 2011, Charo returned to the Drag Race universe as a judge on the "Naughty Nurses" episode of RuPaul's Drag U, a spin-off where drag queens mentor women to embrace their inner divas. Her role as a judge allowed her to impart her experience and perspective, further solidifying her connection to the drag community.

More recently, in 2024, Charo made a guest appearance on RuPaul's Drag Race Season 16, Episode 6, titled "Welcome to the DollHouse." In this episode, she participated in a mini-challenge where contestants engaged in "quick flamenco drag," highlighting her Spanish heritage and the show's celebration of diverse cultures.

Her recurring appearances reflect her enduring popularity and the mutual respect between her and the drag community.